Cologne ▸ Prague
Prague ▸ Cologne ⇄6.1 a dayfastest 9h25☾ 2 overnight busesFlixBus🇩🇪 Germany → 🇨🇿 Czechia
Direct buses · no change
CologneLeverkusenDüsseldorfEssenBochumDortmundPrague· 536 km as the crow flies
- 03:10 → 13:30FlixBus N84Cologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Bonn, Frankfurt, Erlangen, Nuremberg10h204 stops
- 08:35 → 19:35FlixBus 084Cologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Frankfurt, Wertheim, Würzburg, Nuremberg…11h007 stopsRuns: DailyBook on FlixBus ↗
- 09:20 → 21:10FlixBus 264Cologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Leverkusen, Dortmund, Kassel, Göttingen…11h508 stopsRuns: Mon, Tue, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
- 10:35 → 21:30FlixBus 084Cologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Frankfurt, Würzburg, Erlangen, Nuremberg10h555 stopsRuns: Daily until Sat 14 Nov, not Mon 9 Nov, Tue 10 Nov, Wed 11 NovBook on FlixBus ↗
- 11:20 → 20:45FlixBus N870Cologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Frankfurt, Nuremberg9h252 stops
- 11:35 → 21:00FlixBus N870Cologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Frankfurt, Nuremberg9h252 stops
- 11:58 → 21:23FlixBus N870Cologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Frankfurt, Nuremberg9h252 stops
- 12:05 → 21:30FlixBus N870Cologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Frankfurt, Nuremberg9h252 stopsRuns: Tue to Fri (some weeks)Book on FlixBus ↗
- 13:05 → 22:30FlixBus N870Cologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Frankfurt, Nuremberg9h252 stops
- 13:25 → 22:50FlixBus N870Cologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Frankfurt, Nuremberg9h252 stopsRuns: Mon, Sat (some weeks)Book on FlixBus ↗
- 21:00 → 06:55+1FlixBus N84 ☾ OvernightCologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Bonn, Frankfurt, Würzburg, Nuremberg9h555 stops
- 22:10 → 10:10+1FlixBus N23 ☾ OvernightCologne Airport CGN (Terminal 2) → Prague (Central Bus Station Florenc) · via Leverkusen, Düsseldorf, Essen, Bochum…12h008 stopsRuns: Mon, Thu, Fri, Sat, Sun (some weeks)The night the clocks change (Sat 24 Oct: 22:10 → 09:10+1)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and FlixBus UK (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Cologne to Prague?
Yes. 6.1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Cologne to Prague?
The fastest takes 9h25; the slowest 12h00, for 536 km as the crow flies.
When do the buses leave?
The earliest leaves at 03:10 and the latest at 22:10, local time in Cologne. Not every bus runs every day: pick a date above.
Is there a night bus from Cologne to Prague?
Yes: 2 overnight departures in the timetable, for example 21:00 arriving 06:55 the next morning.