Florence to Lyon bus: 4.6 a day, fastest 10h40

4.6 a dayfastest 10h40☾ 3 overnight busesBlaBlaCar Bus, FlixBus🇮🇹 Italy → 🇫🇷 France

Direct buses · no change

FlorenceBolognaMilanTurinChambéryLyon· 550 km as the crow flies

07:30 → 18:10
FlixBus 1501
Florence (Villa Costanza) → Lyon (Gerland Bus Station) · via Genoa, Turin, Grenoble
10h403 stops
Runs: DailyBook on FlixBus ↗
12:00 → 22:40
FlixBus 516
Florence (Villa Costanza) → Lyon (Gerland Bus Station) · via Genoa, Turin
10h402 stops
Runs: Mon, Thu, Fri, Sat, SunBook on FlixBus ↗
12:30 → 23:45
FlixBus N521
Florence (Villa Costanza) → Lyon (Gerland Bus Station) · via Bologna, Turin
11h153 stops
Runs: DailyBook on FlixBus ↗
14:15 → 01:20⁺¹
BlaBlaCar Bus
Florence - Villa Constanza Bus Station → Lyon - Gerland Bus Station · via Bologna, Milan, Turin, Chambéry
11h054 stops
Runs: Sun (some weeks)Book on BlaBlaCar Bus ↗
18:45 → 06:30⁺¹
FlixBus N527 ☾ Overnight
Florence (Villa Costanza) → Lyon (Gerland Bus Station) · via Bologna, Milan, Turin, Chambéry
11h454 stops
Runs: Daily except TueThe night the clocks change (Sat 24 Oct: 18:45 → 05:30+1)Book on FlixBus ↗
19:10 → 06:05⁺¹
BlaBlaCar Bus ☾ Overnight
Florence - Villa Constanza Bus Station → Lyon - Gerland Bus Station · via Bologna, Turin
10h552 stops
Runs: Only Sun 25 Octthe open data has only these datesBook on BlaBlaCar Bus ↗
21:05 → 08:45⁺¹
FlixBus N580 ☾ Overnight
Florence (Villa Costanza) → Lyon (Gerland Bus Station) · via Bologna, Genoa, Turin, Chambéry
11h404 stops
Runs: Wed to SunThe night the clocks change (Sat 24 Oct: 21:05 → 07:45+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and BlaBlaCar Bus (file of 18 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

Fastest door to door: the plane (4h25). The bus takes 7h11 longer.

Bus · fastest direct11h36

To Florence (Villa Costanza)24 min
At the stop before departure15 min
FlixBus 150110h40
From Lyon (Gerland Bus Station)17 min

Plane · nonstop FLR to LYS4h25

To Florence (FLR)20 min
Check-in & security1h30
Flight FLR to LYS1h25
Landing to exit20 min
From LYS50 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance.

Train instead?

No direct train from Florence to Lyon in pickthetrain's timetables: the bus is the no-change way.

Where Florence goes by direct train ↗

Flying instead?

1 airline fly Florence to Lyon nonstop. Book on the airline's own site:

Volotea seasonalFLR→LYSBook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Florence to Lyon?

Yes. 4.6 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Florence to Lyon?

The fastest takes 10h40; the slowest 11h45, for 550 km as the crow flies.

When do the buses leave?

The earliest leaves at 07:30 and the latest at 21:05, local time in Florence. Not every bus runs every day: pick a date above.

Is there a night bus from Florence to Lyon?

Yes: 3 overnight departures in the timetable, for example 18:45 arriving 06:30 the next morning.

Florence ▸ Lyon

Direct buses · no change

Quick answers

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