Frankfurt ▸ Mestre
Mestre ▸ Frankfurt ⇄2.4 a dayfastest 12h10☾ 3 overnight busesFlixBus🇩🇪 Germany → 🇮🇹 Italy
Direct buses · no change
FrankfurtHeidelbergKarlsruheStuttgartUlmMunichMestre· 579 km as the crow flies
- 20:10 → 10:30+1FlixBus N277 ☾ OvernightFrankfurt central train station → Venice Mestre (Stazione FS) · via Heidelberg, Karlsruhe, Stuttgart, Ulm…14h2011 stopsRuns: Mon, Tue, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 20:10 → 09:30+1)Book on FlixBus ↗
- 20:10 → 11:25+1FlixBus N277 ☾ OvernightFrankfurt central train station → Venice (Marco Polo Airport) · via Heidelberg, Karlsruhe, Stuttgart, Ulm…15h1513 stopsRuns: Mon, Tue, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 20:10 → 10:25+1)Book on FlixBus ↗
- 20:30 → 08:40+1FlixBus N28 ☾ OvernightFrankfurt Airport (P36, Terminal 1) → Venice Mestre (Stazione FS) · via Nuremberg, Munich, Verona12h103 stops
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Frankfurt to Mestre?
Yes. 2.4 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Frankfurt to Mestre?
The fastest takes 12h10; the slowest 15h15, for 579 km as the crow flies.
When do the buses leave?
The earliest leaves at 20:10 and the latest at 20:30, local time in Frankfurt. Not every bus runs every day: pick a date above.
Is there a night bus from Frankfurt to Mestre?
Yes: 3 overnight departures in the timetable, for example 20:10 arriving 10:30 the next morning.