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Direct buses › From Frankfurt

Frankfurt ▸ San Severo

San Severo ▸ Frankfurt ⇄
1 a dayfastest 20h40☾ 1 overnight busFlixBus🇩🇪 Germany → 🇮🇹 Italy

Direct buses · no change

FrankfurtKarlsruheStuttgartUlmMunichBolognaSan Severo· 1,070 km as the crow flies
  • 15:15 → 11:55+1
    FlixBus N422 ☾ Overnight
    Frankfurt central train station → San Severo · via Karlsruhe, Stuttgart, Ulm, Munich…
    20h408 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 15:15 → 10:55+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Frankfurt to San Severo?

Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Frankfurt to San Severo?

The fastest takes 20h40; the slowest 20h40, for 1,070 km as the crow flies.

Is there a night bus from Frankfurt to San Severo?

Yes: 1 overnight departure in the timetable, for example 15:15 arriving 11:55 the next morning.

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