Leverkusen ▸ Prague
Prague ▸ Leverkusen ⇄3.5 a dayfastest 11h10☾ 1 overnight busFlixBus🇩🇪 Germany → 🇨🇿 Czechia
Direct buses · no change
LeverkusenSiegenGießenAlsfeldErfurtJenaPrague· 535 km as the crow flies
- 08:00 → 19:10FlixBus 020Leverkusen (Mitte station) → Prague (Central Bus Station Florenc) · via Siegen, Gießen, Alsfeld, Erfurt…11h108 stopsRuns: Mon, Tue, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
- 09:50 → 21:10FlixBus 264Leverkusen (Mitte station) → Prague (Central Bus Station Florenc) · via Dortmund, Kassel, Göttingen, Leipzig…11h207 stopsRuns: Mon, Tue, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
- 09:55 → 21:30FlixBus 084Leverkusen (Mitte station) → Prague (Central Bus Station Florenc) · via Cologne, Frankfurt, Würzburg, Erlangen…11h356 stopsRuns: Daily until Sat 14 Nov, not Mon 9 Nov, Tue 10 Nov, Wed 11 NovBook on FlixBus ↗
- 22:45 → 10:10+1FlixBus N23 ☾ OvernightLeverkusen (Mitte station) → Prague (Central Bus Station Florenc) · via Düsseldorf, Essen, Bochum, Dortmund…11h257 stopsRuns: Mon, Thu, Fri, Sat, Sun (some weeks)The night the clocks change (Sat 24 Oct: 22:45 → 09:10+1)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Leverkusen to Prague?
Yes. 3.5 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Leverkusen to Prague?
The fastest takes 11h10; the slowest 11h35, for 535 km as the crow flies.
When do the buses leave?
The earliest leaves at 08:00 and the latest at 22:45, local time in Leverkusen. Not every bus runs every day: pick a date above.
Is there a night bus from Leverkusen to Prague?
Yes: 1 overnight departure in the timetable, for example 22:45 arriving 10:10 the next morning.