Lyon ▸ Plzeň
Plzeň ▸ Lyon ⇄1 a dayfastest 15h50☾ 1 overnight busFlixBus🇫🇷 France → 🇨🇿 Czechia
Direct buses · no change
LyonChalon-sur-SaôneBelfortMulhouseColmarStrasbourgPlzeň· 777 km as the crow flies
- 22:00 → 13:50+1FlixBus N1315 ☾ OvernightLyon (Gerland Bus Station) → Plzeň (central bus station) · via Chalon-sur-Saône, Belfort, Mulhouse, Colmar…15h5013 stops
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Lyon to Plzeň?
Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Lyon to Plzeň?
The fastest takes 15h50; the slowest 15h50, for 777 km as the crow flies.
Is there a night bus from Lyon to Plzeň?
Yes: 1 overnight departure in the timetable, for example 22:00 arriving 13:50 the next morning.