Mainz to Brussels bus: 1 a day, fastest 5h50

1 a dayfastest 5h50FlixBus🇩🇪 Germany → 🇧🇪 Belgium

Direct buses · no change

MainzBingenCoblenzAachenBrussels· 295 km as the crow flies

12:05 → 17:55
FlixBus N1310
Mainz central train station (exit West) → Brussels-North train station · via Bingen, Coblenz, Aachen
5h503 stops
Runs: DailyThe night the clocks change (Sun 25 Oct: 11:05 → 16:55)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

Fastest door to door: the plane (4h25). The bus takes 2h09 longer.

Bus · fastest direct6h34

To Mainz central train station (exit West)16 min
At the stop before departure15 min
FlixBus N13105h50
From Brussels-North train station13 min

Plane · nonstop FRA to BRU4h25

To Frankfurt (FRA)55 min
Check-in & security1h30
Flight FRA to BRU1h05
Landing to exit20 min
From BRU35 min

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance.

Flying instead?

2 airlines fly Mainz to Brussels nonstop. Book on the airline's own site:

Brussels AirlinesFRA→BRUBook direct ↗
LufthansaFRA→BRUBook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Mainz to Brussels?

Yes. 1 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Mainz to Brussels?

The fastest takes 5h50; the slowest 5h50, for 295 km as the crow flies.

Is there a night bus from Mainz to Brussels?

Not an overnight one: every bus here travels by day or evening.

Mainz ▸ Brussels

Direct buses · no change

Quick answers

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