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Direct buses › From Mestre

Mestre ▸ Prague

Prague ▸ Mestre ⇄
2.2 a dayfastest 11h45☾ 2 overnight busesFlixBus🇮🇹 Italy → 🇨🇿 Czechia

Direct buses · no change

MestreUdineVillachSpittal an der DrauBischofshofenSalzburgPrague· 536 km as the crow flies
  • 00:50 → 13:45
    FlixBus N1533 ☾ Overnight
    Venice Mestre (Stazione FS) → Prague (Main Railway Station) · via Portogruaro, Udine, Klagenfurt, Graz…
    12h556 stops
    Runs: DailyThe night the clocks change (Sun 25 Oct: 00:50 → 12:45)Book on FlixBus ↗
  • 09:10 → 20:55
    FlixBus 861
    Venice Mestre (Stazione FS) → Prague (Central Bus Station Florenc) · via Udine, Villach, Salzburg, Linz…
    11h456 stops
    Runs: Daily until Sun 1 NovBook on FlixBus ↗
  • 17:20 → 05:45+1
    FlixBus 1308 ☾ Overnight
    Venice Mestre (Stazione FS) → Prague (Central Bus Station Florenc) · via Udine, Villach, Spittal an der Drau, Bischofshofen…
    12h257 stops
    Runs: Mon, Thu, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 17:20 → 04:45+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Mestre to Prague?

Yes. 2.2 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Mestre to Prague?

The fastest takes 11h45; the slowest 12h55, for 536 km as the crow flies.

When do the buses leave?

The earliest leaves at 00:50 and the latest at 17:20, local time in Mestre. Not every bus runs every day: pick a date above.

Is there a night bus from Mestre to Prague?

Yes: 2 overnight departures in the timetable, for example 00:50 arriving 13:45.

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