Milan ▸ Brussels
Brussels ▸ Milan ⇄Direct buses · no change
- 15:20 → 04:55+1BlaBlaCar Bus ☾ OvernightMilan - Lampugnano Bus Station → Brussels - Midi Train Station · via Lugano, Zurich, Basel, Saint-Louis…13h357 stopsRuns: Mon, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 15:20 → 03:55+1)Book on BlaBlaCar Bus ↗
- 19:40 → 08:40+1FlixBus N836 ☾ OvernightMilan (Lampugnano bus station) → Brussels-North train station · via Basel, Nancy, Luxembourg13h003 stopsRuns: Mon, Thu, Fri, Sat, Sun (some weeks)The night the clocks change (Sat 24 Oct: 19:40 → 07:40+1)Book on FlixBus ↗
- 19:55 → 08:40+1BlaBlaCar Bus ☾ OvernightMilan - Lampugnano Bus Station → Brussels - Midi Train Station · via Lugano, Zurich, Basel, Metz…12h455 stopsRuns: Mon, Tue, Fri, Sat, Sun (some weeks)The night the clocks change (Sat 24 Oct: 19:55 → 07:40+1)Book on BlaBlaCar Bus ↗
- 22:45 → 11:35+1FlixBus N846 ☾ OvernightMilan (Lampugnano bus station) → Brussels-North train station · via Luzern, Basel, Strasbourg, Saarbrücken12h504 stops
Local times at each stop. Times from official open data: BlaBlaCar Bus (file of 18 Oct 2026) and FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Milan to Brussels?
Yes. 2.8 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Milan to Brussels?
The fastest takes 12h45; the slowest 13h35, for 698 km as the crow flies.
When do the buses leave?
The earliest leaves at 15:20 and the latest at 22:45, local time in Milan. Not every bus runs every day: pick a date above.
Is there a night bus from Milan to Brussels?
Yes: 4 overnight departures in the timetable, for example 15:20 arriving 04:55 the next morning.