Milan ▸ Düsseldorf
Düsseldorf ▸ Milan ⇄2.9 a dayfastest 13h00☾ 3 overnight busesFlixBus🇮🇹 Italy → 🇩🇪 Germany
Direct buses · no change
MilanZurichBaselFreiburgStrasbourgSaarbrückenDüsseldorf· 665 km as the crow flies
- 16:45 → 08:05+1FlixBus N11 ☾ OvernightMilan (Lampugnano bus station) → Düsseldorf central bus station · via Zurich, Basel, Freiburg, Strasbourg…15h209 stopsRuns: Mon, Thu, Fri, Sat, Sun (some weeks)The night the clocks change (Sat 24 Oct: 16:45 → 07:05+1)Book on FlixBus ↗
- 20:25 → 09:25+1FlixBus N487 ☾ OvernightMilan (Lampugnano bus station) → Düsseldorf central bus station · via Basel, Karlsruhe, Mannheim, Frankfurt…13h005 stops
- 23:45 → 14:00+1FlixBus N177 ☾ OvernightMilan (Lampugnano bus station) → Düsseldorf central bus station · via Zurich, Tübingen, Stuttgart, Karlsruhe…14h159 stops
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Milan to Düsseldorf?
Yes. 2.9 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Milan to Düsseldorf?
The fastest takes 13h00; the slowest 15h20, for 665 km as the crow flies.
When do the buses leave?
The earliest leaves at 16:45 and the latest at 23:45, local time in Milan. Not every bus runs every day: pick a date above.
Is there a night bus from Milan to Düsseldorf?
Yes: 3 overnight departures in the timetable, for example 16:45 arriving 08:05 the next morning.