Milan to Luzern bus: 3.3 a day, fastest 3h20

3.3 a dayfastest 3h20FlixBus🇮🇹 Italy → 🇨🇭 Switzerland

Direct buses · no change

MilanComoLuganoLuzern· 189 km as the crow flies

01:00 → 04:20
FlixBus N401
Milan (Lampugnano bus station) → Luzern (Landenberg)
3h20nonstop
Runs: DailyThe night the clocks change (Sun 25 Oct: 01:00 → 03:20)Book on FlixBus ↗
12:15 → 16:25
FlixBus 439
Milan (Lampugnano bus station) → Luzern (Landenberg)
4h10nonstop
Runs: Mon, Thu, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
17:20 → 21:35
FlixBus 1524
Milan (Lampugnano bus station) → Luzern (Landenberg) · via Como, Lugano
4h152 stops
Runs: Daily except MonBook on FlixBus ↗
22:45 → 02:10⁺¹
FlixBus N846
Milan (Lampugnano bus station) → Luzern (Landenberg)
3h25nonstop
Runs: Mon, Fri, Sat, SunBook on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

The bus is the fastest way door to door

Bus · fastest direct4h08

To Milan (Lampugnano bus station)22 min
At the stop before departure15 min
FlixBus N4013h20
From Luzern (Landenberg)11 min

Plane · nonstop MXP to ZRH4h50

To Milan Malpensa (MXP)55 min
Check-in & security1h30
Flight MXP to ZRH1h00
Landing to exit20 min
From ZRH1h05

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance.

Flying instead?

2 airlines fly Milan to Luzern nonstop. Book on the airline's own site:

Ethiopian AirlinesMXP→ZRHBook direct ↗
Swiss International Air LinesMXP→ZRHBook direct ↗

Compare on picktheflight ↗

Quick answers

Is there a direct bus from Milan to Luzern?

Yes. 3.3 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Milan to Luzern?

The fastest takes 3h20; the slowest 4h15, for 189 km as the crow flies.

When do the buses leave?

The earliest leaves at 01:00 and the latest at 22:45, local time in Milan. Not every bus runs every day: pick a date above.

Is there a night bus from Milan to Luzern?

Not an overnight one: every bus here travels by day or evening.

Milan ▸ Luzern

Direct buses · no change

Quick answers

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