Zurich ▸ Brussels
Brussels ▸ Zurich ⇄Direct buses · no change
- 09:25 → 20:35FlixBus 299Zurich Bus Station → Brussels-North train station · via Basel, Freiburg, Strasbourg, Saarbrücken…11h105 stopsRuns: Mon, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
- 19:50 → 04:55+1BlaBlaCar Bus ☾ OvernightZürich → Brussels - Midi Train Station · via Basel, Saint-Louis, Colmar, Strasbourg…9h055 stopsRuns: Mon, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 19:50 → 03:55+1)Book on BlaBlaCar Bus ↗
- 23:59 → 08:40+1BlaBlaCar Bus ☾ OvernightZürich → Brussels - Midi Train Station · via Basel, Metz, Luxembourg8h413 stopsRuns: Mon, Tue, Fri, Sat, Sun (some weeks)The night the clocks change (Sat 24 Oct: 23:59 → 07:40+1)Book on BlaBlaCar Bus ↗
Twiliner runs a night bus on its Zurich to Amsterdam line, which calls at Zurich and Brussels. It publishes no open timetable, so we show no times: check times, and which stops it sells between, on its own site.
Times and tickets on Twiliner ↗ · About Twiliner · checked 18 Oct 2026
Local times at each stop. Times from official open data: BlaBlaCar Bus (file of 18 Oct 2026) and FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Zurich to Brussels?
Yes. 2.2 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Zurich to Brussels?
The fastest takes 8h41; the slowest 11h10, for 493 km as the crow flies.
When do the buses leave?
The earliest leaves at 09:25 and the latest at 23:59, local time in Zurich. Not every bus runs every day: pick a date above.
Is there a night bus from Zurich to Brussels?
Yes: 2 overnight departures in the timetable, for example 19:50 arriving 04:55 the next morning.