Brussels ▸ Karlsruhe
Karlsruhe ▸ Brussels ⇄1.2 a dayfastest 7h15☾ 1 overnight busFlixBus🇧🇪 Belgium → 🇩🇪 Germany
Direct buses · no change
BrusselsNamurLuxembourgMerzigSaarbrückenZweibrückenKarlsruhe· 355 km as the crow flies
- 07:00 → 14:15FlixBus 1929Brussels-North train station → Karlsruhe central train station · via Namur, Luxembourg, Merzig, Saarbrücken…7h155 stopsRuns: Mon (some weeks)Book on FlixBus ↗
- 22:55 → 06:25+1FlixBus N136 ☾ OvernightBrussels-North train station → Karlsruhe central train station · via Luxembourg, Metz, Strasbourg7h303 stops
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Brussels to Karlsruhe?
Yes. 1.2 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Brussels to Karlsruhe?
The fastest takes 7h15; the slowest 7h30, for 355 km as the crow flies.
When do the buses leave?
The earliest leaves at 07:00 and the latest at 22:55, local time in Brussels. Not every bus runs every day: pick a date above.
Is there a night bus from Brussels to Karlsruhe?
Yes: 1 overnight departure in the timetable, for example 22:55 arriving 06:25 the next morning.