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Direct buses › From Frankfurt

Frankfurt ▸ Lyon

Lyon ▸ Frankfurt ⇄
3.5 a dayfastest 10h00☾ 3 overnight busesBlaBlaCar Bus, FlixBus🇩🇪 Germany → 🇫🇷 France

Direct buses · no change

FrankfurtMannheimKarlsruheFreiburgBaselBernLyon· 563 km as the crow flies
  • 08:15 → 20:50
    FlixBus 122
    Frankfurt central train station → Lyon (Gerland Bus Station) · via Mannheim, Karlsruhe, Freiburg, Basel…
    12h357 stops
    Runs: DailyBook on FlixBus ↗
  • 08:55 → 20:45
    BlaBlaCar Bus
    Frankfurt - Main Bus Station → Lyon - Gerland Bus Station · via Darmstadt, Karlsruhe, Strasbourg, Nancy
    11h505 stops
    Runs: Wed, Fri, Sun (some weeks)Book on BlaBlaCar Bus ↗
  • 18:30 → 05:10+1
    BlaBlaCar Bus ☾ Overnight
    Frankfurt - Main Bus Station → Lyon - Gerland Bus Station · via Mannheim, Karlsruhe, Strasbourg, Colmar…
    10h406 stops
    Runs: Thu, Fri, SunBook on BlaBlaCar Bus ↗
  • 19:05 → 05:05+1
    FlixBus N235 ☾ Overnight
    Frankfurt central train station → Lyon (Gerland Bus Station) · via Saarbrücken, Metz, Nancy
    10h004 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 19:05 → 04:05+1)Book on FlixBus ↗
  • 22:45 → 10:30+1
    FlixBus N122 ☾ Overnight
    Frankfurt central train station → Lyon (Gerland Bus Station) · via Mannheim, Karlsruhe, Freiburg, Basel…
    11h458 stops
    Runs: Mon, Thu, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 22:45 → 09:30+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and BlaBlaCar Bus (file of 18 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Frankfurt to Lyon?

Yes. 3.5 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Frankfurt to Lyon?

The fastest takes 10h00; the slowest 12h35, for 563 km as the crow flies.

When do the buses leave?

The earliest leaves at 08:15 and the latest at 22:45, local time in Frankfurt. Not every bus runs every day: pick a date above.

Is there a night bus from Frankfurt to Lyon?

Yes: 3 overnight departures in the timetable, for example 18:30 arriving 05:10 the next morning.

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