Heidelberg to Milan bus: 3.8 a day, fastest 8h56

3.8 a dayfastest 8h56☾ 2 overnight busesFlixBus🇩🇪 Germany → 🇮🇹 Italy

Direct buses · no change

HeidelbergKarlsruheFreiburgLörrachZurichMilan· 440 km as the crow flies

02:19 → 11:15
FlixBus N07 ☾ Overnight
Heidelberg Pre Waypoint → Milan (Lampugnano bus station) · via Karlsruhe, Freiburg, Zurich
8h565 stops
Runs: DailyThe night the clocks change (Sun 25 Oct: 02:19 → 10:15)Book on FlixBus ↗
09:44 → 19:15
FlixBus 476
Heidelberg Pre Waypoint → Milan (Lampugnano bus station) · via Karlsruhe, Freiburg, Lörrach, Zurich
9h316 stops
Runs: Mon, Tue, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
12:04 → 22:00
FlixBus 107
Heidelberg Pre Waypoint → Milan (Lampugnano bus station) · via Freiburg, Basel, Zurich
9h565 stops
Runs: DailyBook on FlixBus ↗
22:04 → 07:10⁺¹
FlixBus N177 ☾ Overnight
Heidelberg Pre Waypoint → Milan (Lampugnano bus station) · via Karlsruhe, Stuttgart, Tübingen, Zurich
9h066 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 22:04 → 06:10+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Heidelberg to Milan?

Yes. 3.8 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Heidelberg to Milan?

The fastest takes 8h56; the slowest 9h56, for 440 km as the crow flies.

When do the buses leave?

The earliest leaves at 02:19 and the latest at 22:04, local time in Heidelberg. Not every bus runs every day: pick a date above.

Is there a night bus from Heidelberg to Milan?

Yes: 2 overnight departures in the timetable, for example 02:19 arriving 11:15.

Heidelberg ▸ Milan

Direct buses · no change

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