Milan to Heidelberg bus: 3.8 a day, fastest 8h54

3.8 a dayfastest 8h54☾ 2 overnight busesFlixBus🇮🇹 Italy → 🇩🇪 Germany

Direct buses · no change

MilanZurichLörrachFreiburgKarlsruheHeidelberg· 440 km as the crow flies

07:15 → 16:29
FlixBus 476
Milan (Lampugnano bus station) → Heidelberg Pre Waypoint · via Zurich, Lörrach, Freiburg, Karlsruhe
9h144 stops
Runs: Mon, Thu, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
11:30 → 21:34
FlixBus 107
Milan (Lampugnano bus station) → Heidelberg Pre Waypoint · via Zurich, Basel, Freiburg, Rust
10h044 stops
Runs: DailyBook on FlixBus ↗
19:00 → 03:54⁺¹
FlixBus N07 ☾ Overnight
Milan (Lampugnano bus station) → Heidelberg Pre Waypoint · via Zurich, Freiburg, Karlsruhe
8h543 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 19:00 → 02:54+1)Book on FlixBus ↗
23:45 → 09:09⁺¹
FlixBus N177 ☾ Overnight
Milan (Lampugnano bus station) → Heidelberg Pre Waypoint · via Zurich, Tübingen, Stuttgart, Karlsruhe
9h244 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 23:45 → 08:09+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Milan to Heidelberg?

Yes. 3.8 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Milan to Heidelberg?

The fastest takes 8h54; the slowest 10h04, for 440 km as the crow flies.

When do the buses leave?

The earliest leaves at 07:15 and the latest at 23:45, local time in Milan. Not every bus runs every day: pick a date above.

Is there a night bus from Milan to Heidelberg?

Yes: 2 overnight departures in the timetable, for example 19:00 arriving 03:54 the next morning.

Milan ▸ Heidelberg

Direct buses · no change

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