Karlsruhe ▸ Mestre
Mestre ▸ Karlsruhe ⇄1.4 a dayfastest 11h50☾ 2 overnight busesFlixBus🇩🇪 Germany → 🇮🇹 Italy
Direct buses · no change
KarlsruheStuttgartUlmMunichBolzanoTrentoMestre· 487 km as the crow flies
- 22:40 → 10:30+1FlixBus N277 ☾ OvernightKarlsruhe central train station → Venice Mestre (Stazione FS) · via Stuttgart, Ulm, Munich, Bolzano…11h506 stopsRuns: Mon, Tue, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 22:40 → 09:30+1)Book on FlixBus ↗
- 22:40 → 11:25+1FlixBus N277 ☾ OvernightKarlsruhe central train station → Venice (Marco Polo Airport) · via Stuttgart, Ulm, Munich, Bolzano…12h458 stopsRuns: Mon, Tue, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 22:40 → 10:25+1)Book on FlixBus ↗
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Karlsruhe to Mestre?
Yes. 1.4 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Karlsruhe to Mestre?
The fastest takes 11h50; the slowest 12h45, for 487 km as the crow flies.
When do the buses leave?
The earliest leaves at 22:40 and the latest at 22:40, local time in Karlsruhe. Not every bus runs every day: pick a date above.
Is there a night bus from Karlsruhe to Mestre?
Yes: 2 overnight departures in the timetable, for example 22:40 arriving 10:30 the next morning.