Milan to Mannheim bus: 4 a day, fastest 8h20

4 a dayfastest 8h20☾ 4 overnight busesFlixBus🇮🇹 Italy → 🇩🇪 Germany

Direct buses · no change

MilanZurichTübingenStuttgartKarlsruheHeidelbergMannheim· 451 km as the crow flies

01:15 → 12:15
FlixBus N77 ☾ Overnight
Milan (Lampugnano bus station) → Mannheim central bus station · via Bregenz, Ulm, Stuttgart, Karlsruhe
11h004 stops
Runs: DailyThe night the clocks change (Sun 25 Oct: 01:15 → 11:15)Book on FlixBus ↗
19:00 → 04:25⁺¹
FlixBus N07 ☾ Overnight
Milan (Lampugnano bus station) → Mannheim central bus station · via Zurich, Freiburg, Karlsruhe, Heidelberg
9h256 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 19:00 → 03:25+1)Book on FlixBus ↗
20:25 → 04:45⁺¹
FlixBus N487 ☾ Overnight
Milan (Lampugnano bus station) → Mannheim central bus station · via Basel, Karlsruhe
8h202 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 20:25 → 03:45+1)Book on FlixBus ↗
23:45 → 09:40⁺¹
FlixBus N177 ☾ Overnight
Milan (Lampugnano bus station) → Mannheim central bus station · via Zurich, Tübingen, Stuttgart, Karlsruhe…
9h557 stops
Runs: DailyThe night the clocks change (Sat 24 Oct: 23:45 → 08:40+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Bus, train or plane

☾ Overnight: leave 20:25, arrive 04:45

The train is 2h11 quicker door to door, but the night bus spends your night on the road instead of a day.

Bus · fastest direct9h10

To Milan (Lampugnano bus station)22 min
At the stop before departure15 min
FlixBus N4878h20
From Mannheim central bus station13 min

Train · fastest direct6h59

To Milano Centrale1 min
Before departure10 min
EC 1506h48

City centre to city centre. Getting to stops, stations and airports: typical public-transport times (estimates). Bus: be at the stop 15 min before. Plane: check-in and security 1h30 before, then getting out after landing; flight time typical for the distance. Train: pickthetrain's door-to-door time.

Train instead?

1 a daydirect trains, fastest 6h48

Trenitalia. No change of train, from the operators' official timetables.

See the trains on pickthetrain ↗

Quick answers

Is there a direct bus from Milan to Mannheim?

Yes. 4 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Milan to Mannheim?

The fastest takes 8h20; the slowest 11h00, for 451 km as the crow flies.

When do the buses leave?

The earliest leaves at 01:15 and the latest at 23:45, local time in Milan. Not every bus runs every day: pick a date above.

Is there a night bus from Milan to Mannheim?

Yes: 4 overnight departures in the timetable, for example 01:15 arriving 12:15.

Milan ▸ Mannheim

Direct buses · no change

Quick answers

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