Mannheim ▸ Milan
Milan ▸ Mannheim ⇄4 a dayfastest 8h20☾ 3 overnight busesFlixBus🇩🇪 Germany → 🇮🇹 Italy
Direct buses · no change
MannheimHeidelbergKarlsruheStuttgartTübingenZurichMilan· 451 km as the crow flies
- 02:00 → 11:15FlixBus N07 ☾ OvernightMannheim central bus station → Milan (Lampugnano bus station) · via Heidelberg, Karlsruhe, Freiburg, Zurich9h156 stops
- 08:30 → 16:50FlixBus N487Mannheim central bus station → Milan (Lampugnano bus station) · via Karlsruhe, Basel8h202 stops
- 19:00 → 05:05+1FlixBus N77 ☾ OvernightMannheim central bus station → Milan (Lampugnano bus station) · via Karlsruhe, Stuttgart, Ulm, Bregenz10h054 stops
- 21:40 → 07:10+1FlixBus N177 ☾ OvernightMannheim central bus station → Milan (Lampugnano bus station) · via Heidelberg, Karlsruhe, Stuttgart, Tübingen…9h307 stops
Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.
Quick answers
Is there a direct bus from Mannheim to Milan?
Yes. 4 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).
How long is the bus from Mannheim to Milan?
The fastest takes 8h20; the slowest 10h05, for 451 km as the crow flies.
When do the buses leave?
The earliest leaves at 02:00 and the latest at 21:40, local time in Mannheim. Not every bus runs every day: pick a date above.
Is there a night bus from Mannheim to Milan?
Yes: 3 overnight departures in the timetable, for example 02:00 arriving 11:15.