pickthebus

Mannheim ▸ Lyon

Lyon ▸ Mannheim ⇄
2.1 a dayfastest 9h05☾ 2 overnight busesBlaBlaCar Bus, FlixBus🇩🇪 Germany → 🇫🇷 France

Direct buses · no change

MannheimKarlsruheFreiburgBaselBernLausanneLyon· 496 km as the crow flies
  • 09:20 → 20:50
    FlixBus 122
    Mannheim central bus station → Lyon (Gerland Bus Station) · via Karlsruhe, Freiburg, Basel, Bern…
    11h306 stops
  • 20:05 → 05:10+1
    BlaBlaCar Bus ☾ Overnight
    Mannheim - Bus Station → Lyon - Gerland Bus Station · via Karlsruhe, Strasbourg, Colmar, Mulhouse
    9h054 stops
    Runs: Thu, Fri, SunBook on BlaBlaCar Bus ↗
  • 23:59 → 10:30+1
    FlixBus N122 ☾ Overnight
    Mannheim central bus station → Lyon (Gerland Bus Station) · via Karlsruhe, Freiburg, Basel, Bern…
    10h316 stops
    Runs: Mon, Thu, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 23:59 → 09:30+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and BlaBlaCar Bus (file of 18 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Mannheim to Lyon?

Yes. 2.1 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Mannheim to Lyon?

The fastest takes 9h05; the slowest 11h30, for 496 km as the crow flies.

When do the buses leave?

The earliest leaves at 09:20 and the latest at 23:59, local time in Mannheim. Not every bus runs every day: pick a date above.

Is there a night bus from Mannheim to Lyon?

Yes: 2 overnight departures in the timetable, for example 20:05 arriving 05:10 the next morning.