pickthebus

Prague ▸ Berlin

Berlin ▸ Prague ⇄
24.6 a dayfastest 4h00☾ 3 overnight busesFlixBus🇨🇿 Czechia → 🇩🇪 Germany

Direct buses · no change

PragueKarlovy VaryOstrovOberwiesenthalAnnaberg-BuchholzChemnitzBerlin· 280 km as the crow flies
  • 01:00 → 05:50
    FlixBus N60
    Prague (Main Railway Station) → Berlin Südkreuz train station · via Dresden
    4h503 stops
    Runs: DailyThe night the clocks change (Sun 25 Oct: 01:00 → 04:50)Book on FlixBus ↗
  • 01:25 → 06:45
    FlixBus N1908 ☾ Overnight
    Prague (Main Railway Station) → Berlin central bus station · via Dresden
    5h202 stops
    Runs: Mon, Thu, FriBook on FlixBus ↗
  • 02:00 → 06:35
    FlixBus N260
    Prague (Main Railway Station) → Berlin Südkreuz train station · via Dresden
    4h351 stop
    Runs: Daily except TueThe night the clocks change (Sun 25 Oct: 02:00 → 05:35)Book on FlixBus ↗
  • 02:30 → 07:45
    FlixBus N60 ☾ Overnight
    Prague (Main Railway Station) → Berlin Alexanderplatz · via Dresden
    5h153 stops
    Runs: Mon, Tue, Wed, Sat, SunThe night the clocks change (Sun 25 Oct: 02:30 → 06:45)Book on FlixBus ↗
  • 03:30 → 08:25
    FlixBus N60
    Prague (Main Railway Station) → Berlin Südkreuz train station · via Dresden
    4h553 stops
    Runs: DailyThe night the clocks change (Sun 25 Oct: 02:30 → 07:25)Book on FlixBus ↗
  • 03:45 → 09:45
    FlixBus 1926
    Prague (Central Bus Station Florenc) → Berlin central bus station · via Dresden, Leipzig
    6h002 stops
    Runs: Only Sun 18 Oct, Tue 20 Oct, Fri 23 Oct, Sun 25 Oct, Tue 27 Oct…The night the clocks change (Sun 25 Oct: 02:45 → 08:45)Book on FlixBus ↗
  • 04:00 → 09:05
    FlixBus N260
    Prague (Main Railway Station) → Berlin central bus station · via Dresden
    5h052 stops
    Runs: DailyThe night the clocks change (Sun 25 Oct: 03:00 → 08:05)Book on FlixBus ↗
  • 05:50 → 10:35
    FlixBus N260
    Prague (Main Railway Station) → Berlin Südkreuz train station · via Dresden
    4h452 stops
    Runs: DailyThe night the clocks change (Sun 25 Oct: 04:50 → 09:35)Book on FlixBus ↗
  • 07:00 → 11:05
    FlixBus N132
    Prague (Central Bus Station Florenc) → Berlin Südkreuz train station
    4h05nonstop
    Runs: Thu to Sun (some weeks)Book on FlixBus ↗
  • 07:45 → 14:35
    FlixBus 239
    Prague (Central Bus Station Florenc) → Berlin Südkreuz train station · via Liberec, Zittau, Bautzen, Dresden
    6h505 stops
    Runs: Mon, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
  • 08:00 → 13:00
    FlixBus 170 / 170A
    Prague (Central Bus Station Florenc) → Berlin Alexanderplatz · via Dresden
    5h002 stops
  • 09:00 → 13:35
    FlixBus N160
    Prague (Central Bus Station Florenc) → Berlin Südkreuz train station · via Dresden
    4h352 stops
    Runs: DailyThe night the clocks change (Sun 25 Oct: 08:00 → 12:35)Book on FlixBus ↗
  • 09:15 → 14:20
    FlixBus N958
    Prague (Main Railway Station) → Berlin central bus station
    5h052 stops
    Runs: DailyThe night the clocks change (Sun 25 Oct: 08:15 → 13:20)Book on FlixBus ↗
  • 10:45 → 15:35
    FlixBus 060
    Prague (Main Railway Station) → Berlin Südkreuz train station · via Dresden
    4h503 stops
  • 11:45 → 17:00
    FlixBus 060
    Prague (Main Railway Station) → Berlin central bus station · via Dresden
    5h154 stops
    Runs: Mon, Tue, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
  • 12:45 → 17:35
    FlixBus 060
    Prague (Main Railway Station) → Berlin Südkreuz train station · via Dresden
    4h503 stops
  • 13:25 → 21:05
    FlixBus 860
    Prague (Bus Terminal Roztyly) → Berlin central bus station · via Liberec, Zittau, Görlitz, Dresden
    7h406 stops
    Runs: Mon, Thu, Fri, Sat, SunBook on FlixBus ↗
  • 13:45 → 18:55
    FlixBus 1926
    Prague (Main Railway Station) → Berlin central bus station
    5h101 stop
    Runs: Daily from Thu 5 Nov, not Tue 10 Nov, Wed 11 NovBook on FlixBus ↗
  • 14:10 → 18:40
    FlixBus 260
    Prague (Main Railway Station) → Berlin Südkreuz train station
    4h301 stop
  • 14:45 → 19:35
    FlixBus 060
    Prague (Main Railway Station) → Berlin Südkreuz train station · via Dresden
    4h503 stops
  • 14:55 → 23:05
    FlixBus 910
    Prague (Central Bus Station Florenc) → Berlin central bus station · via Karlovy Vary, Ostrov, Oberwiesenthal, Annaberg-Buchholz…
    8h108 stops
  • 16:10 → 20:40
    FlixBus 260
    Prague (Main Railway Station) → Berlin Südkreuz train station
    4h301 stop
  • 16:45 → 21:35
    FlixBus 060
    Prague (Main Railway Station) → Berlin Südkreuz train station · via Dresden
    4h503 stops
  • 17:30 → 22:25
    FlixBus 260
    Prague (Main Railway Station) → Berlin Alexanderplatz · via Dresden
    4h552 stops
  • 18:00 → 22:00
    FlixBus N32
    Prague (Central Bus Station Florenc) → Berlin Südkreuz train station
    4h00nonstop
    Runs: Wed to Sun (some weeks)Book on FlixBus ↗
  • 18:45 → 23:35
    FlixBus 060
    Prague (Main Railway Station) → Berlin Südkreuz train station · via Dresden
    4h503 stops
  • 20:30 → 01:25+1
    FlixBus N232
    Prague (Central Bus Station Florenc) → Berlin Alexanderplatz · via Dresden
    4h552 stops
    Runs: Daily until Sun 1 Nov, not Tue 20 Oct, Tue 27 OctBook on FlixBus ↗
  • 21:30 → 02:40+1
    FlixBus N70
    Prague (Central Bus Station Florenc) → Berlin Alexanderplatz · via Dresden
    5h103 stops
  • 23:25 → 05:05+1
    FlixBus N360 / N360A ☾ Overnight
    Prague (Main Railway Station) → Berlin Alexanderplatz · via Dresden
    5h404 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 23:25 → 04:05+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Prague to Berlin?

Yes. 24.6 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Prague to Berlin?

The fastest takes 4h00; the slowest 8h10, for 280 km as the crow flies.

When do the buses leave?

The earliest leaves at 01:00 and the latest at 23:25, local time in Prague. Not every bus runs every day: pick a date above.

Is there a night bus from Prague to Berlin?

Yes: 3 overnight departures in the timetable, for example 01:25 arriving 06:45.