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Direct buses › From Prague

Prague ▸ Leipzig

Leipzig ▸ Prague ⇄
8 a dayfastest 3h15FlixBus🇨🇿 Czechia → 🇩🇪 Germany

Direct buses · no change

PragueChomutovMarienbergChemnitzLeipzig· 200 km as the crow flies
  • 01:45 → 05:00
    FlixBus N66
    Prague (Main Railway Station) → Leipzig central train station
    3h15nonstop
    Runs: Mon, Tue, Fri, Sat, Sun (some weeks)The night the clocks change (Sun 25 Oct: 01:45 → 04:00)Book on FlixBus ↗
  • 02:55 → 06:40
    FlixBus N881
    Prague (Main Railway Station) → Leipzig central train station · via Dresden
    3h451 stop
    Runs: Mon, Thu, Fri, Sat, SunThe night the clocks change (Sun 25 Oct: 02:55 → 05:40)Book on FlixBus ↗
  • 03:45 → 07:25
    FlixBus 1926
    Prague (Central Bus Station Florenc) → Leipzig central train station · via Dresden
    3h401 stop
    Runs: Only Sun 18 Oct, Tue 20 Oct, Fri 23 Oct, Sun 25 Oct, Tue 27 Oct…The night the clocks change (Sun 25 Oct: 02:45 → 06:25)Book on FlixBus ↗
  • 09:30 → 13:15
    FlixBus 264
    Prague (Central Bus Station Florenc) → Leipzig central train station · via Dresden
    3h451 stop
    Runs: Mon, Thu, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
  • 10:00 → 13:50
    FlixBus N367
    Prague (Central Bus Station Florenc) → Leipzig central train station · via Dresden
    3h501 stop
    Runs: DailyBook on FlixBus ↗
  • 11:30 → 16:05
    FlixBus 182
    Prague (Central Bus Station Florenc) → Leipzig central train station · via Chomutov, Marienberg, Chemnitz
    4h355 stops
    Runs: Only Mon 2 Nov, Thu 5 Nov, Fri 6 Nov, Sat 7 Nov, Sun 8 Nov…Book on FlixBus ↗
  • 11:35 → 16:10
    FlixBus 182
    Prague (Central Bus Station Florenc) → Leipzig central train station · via Chomutov, Marienberg, Chemnitz
    4h355 stops
    Runs: Daily until Sat 31 OctBook on FlixBus ↗
  • 14:30 → 18:15
    FlixBus 167
    Prague (Central Bus Station Florenc) → Leipzig central train station · via Dresden
    3h451 stop
    Runs: Sun (some weeks)Book on FlixBus ↗
  • 15:45 → 19:45
    FlixBus 167
    Prague (Main Railway Station) → Leipzig central train station · via Dresden
    4h002 stops
    Runs: Mon, Tue, Fri, Sat, Sun (some weeks)Book on FlixBus ↗
  • 18:00 → 21:45
    FlixBus N67
    Prague (Central Bus Station Florenc) → Leipzig central train station · via Dresden
    3h451 stop
    Runs: DailyBook on FlixBus ↗
  • 20:00 → 23:50
    FlixBus N23
    Prague (Central Bus Station Florenc) → Leipzig central train station · via Dresden
    3h501 stop
    Runs: Wed to Sun (some weeks)Book on FlixBus ↗
  • 22:30 → 02:15+1
    FlixBus N67
    Prague (Central Bus Station Florenc) → Leipzig central train station · via Dresden
    3h451 stop
    Runs: Daily until Sun 1 NovBook on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Prague to Leipzig?

Yes. 8 a day on average, with FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Prague to Leipzig?

The fastest takes 3h15; the slowest 4h35, for 200 km as the crow flies.

When do the buses leave?

The earliest leaves at 01:45 and the latest at 22:30, local time in Prague. Not every bus runs every day: pick a date above.

Is there a night bus from Prague to Leipzig?

Not an overnight one: every bus here travels by day or evening.

More from Prague

Every bus from Prague

More to Leipzig

Every bus from Leipzig