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Karlsruhe ▸ Avignon

Avignon ▸ Karlsruhe ⇄
2.1 a dayfastest 10h50☾ 3 overnight busesBlaBlaCar Bus, FlixBus🇩🇪 Germany → 🇫🇷 France

Direct buses · no change

KarlsruheStrasbourgColmarMulhouseBelfortChalon-sur-SaôneAvignon· 626 km as the crow flies
  • 20:20 → 07:15+1
    FlixBus N1135 ☾ Overnight
    Karlsruhe central train station → Avignon (Le Pontet) · via Strasbourg, Freiburg, Mulhouse, Lyon
    10h554 stops
    Runs: Mon, Tue, Fri, Sat, SunThe night the clocks change (Sat 24 Oct: 20:20 → 06:15+1)Book on FlixBus ↗
  • 21:05 → 07:55+1
    BlaBlaCar Bus ☾ Overnight
    Karlsruhe - Central Station South Side → Avignon - Le Pontet - Le Lac Stop · via Strasbourg, Colmar, Mulhouse, Lyon
    10h504 stops
    Runs: Thu, Fri, SunBook on BlaBlaCar Bus ↗
  • 23:55 → 11:15+1
    FlixBus N1315 ☾ Overnight
    Karlsruhe central train station → Avignon (Le Pontet) · via Strasbourg, Colmar, Mulhouse, Belfort…
    11h206 stops
    Runs: DailyThe night the clocks change (Sat 24 Oct: 23:55 → 10:15+1)Book on FlixBus ↗

Local times at each stop. Times from official open data: FlixBus (file of 11 Oct 2026) and BlaBlaCar Bus (file of 18 Oct 2026). Checked Sun 18 Oct 2026; they cover 18 Oct to 14 Nov 2026. Timetables change, so check with the operator before you travel. Contains FlixBus timetable data (FlixMobility, transport.data.gouv.fr), ODbL 1.0. Contains BlaBlaCar Bus timetable data (transport.data.gouv.fr), ODbL 1.0. How we build this.

Quick answers

Is there a direct bus from Karlsruhe to Avignon?

Yes. 2.1 a day on average, with BlaBlaCar Bus and FlixBus, no change of bus (18 Oct to 14 Nov 2026).

How long is the bus from Karlsruhe to Avignon?

The fastest takes 10h50; the slowest 11h20, for 626 km as the crow flies.

When do the buses leave?

The earliest leaves at 20:20 and the latest at 23:55, local time in Karlsruhe. Not every bus runs every day: pick a date above.

Is there a night bus from Karlsruhe to Avignon?

Yes: 3 overnight departures in the timetable, for example 20:20 arriving 07:15 the next morning.